Version 5.4
Bos taurus Gene: BT.24324
Summary
InnateDB Gene IDBG-641870.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.24324
Gene Name amyloid beta A4 precursor protein-binding family B member 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000027569
Encoded Proteins
IDBP-694276
amyloid beta A4 precursor protein-binding family B member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163697:
The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer\'s disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:61362546-61744231
Strand Reverse strand
Band
Transcripts
ENSBTAT00000039647 ENSBTAP00000039437
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008134 transcription factor binding
Biological Process
GO:0001764 neuron migration
GO:0006355 regulation of transcription, DNA-templated
GO:0007050 cell cycle arrest
GO:0007411 axon guidance
GO:0030198 extracellular matrix organization
GO:0030308 negative regulation of cell growth
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000163697
View Gene Order
ENSMUSG00000029207
View Gene Order
Cross-References
SwissProt
TrEMBL F1MDE6
UniProt Splice Variant
Entrez Gene 514013
UniGene Bt.24324
RefSeq NM_001076847 XM_005207856 XM_005207857 XM_005207858 XM_005207859 XM_005207860 XM_005207861 XM_005207862 XM_005207863 XM_005207864 XM_005207865
HUGO HGNC:582
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02017494 DAAA02017495 DAAA02017496 DAAA02017497 DAAA02017498 DAAA02017499 DAAA02017500
GenPept
RNA Seq Atlas 514013

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca