InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: SAG

Summary

InnateDB Gene

IDBG-641875.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SAG

Gene Name

S-arrestin S-arrestin short form

Synonyms

S-AG

Species

Bos taurus

Ensembl Gene

ENSBTAG00000021480

Encoded Proteins

IDBP-694294

S-arrestinS-arrestin short form

IDBP-694295

S-arrestinS-arrestin short form

IDBP-694297

S-arrestinS-arrestin short form

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130561:
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:113633794-113664182

Strand

Forward strand

Band

Transcripts

ENSBTAT00000028633	ENSBTAP00000028633
ENSBTAT00000033205	ENSBTAP00000033126
ENSBTAT00000065854	ENSBTAP00000055008

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.