InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: AHCY

Summary

InnateDB Gene

IDBG-641883.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AHCY

Gene Name

Adenosylhomocysteinase

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000018101

Encoded Proteins

IDBP-694293

Adenosylhomocysteinase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101444:
S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 13:64258560-64274274

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000024092

ENSBTAP00000024092

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.

Predicted by orthology
Total	29 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004013	adenosylhomocysteinase activity
GO:0004455	ketol-acid reductoisomerase activity
GO:0005507	copper ion binding
GO:0016787	hydrolase activity
GO:0043621	protein self-association
GO:0051287	NAD binding

Biological Process

GO:0006730	one-carbon metabolic process
GO:0008652	cellular amino acid biosynthetic process
GO:0019510	S-adenosylhomocysteine catabolic process
GO:0055114	oxidation-reduction process