Bos taurus Gene: BT.21212
Summary
InnateDB Gene IDBG-642489.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.21212
Gene Name bile acyl-CoA synthetase precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015164
Encoded Proteins
bile acyl-CoA synthetase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000083807:
The protein encoded by this gene is an isozyme of very long-chain acyl-CoA synthetase (VLCS). It is capable of activating very long-chain fatty-acids containing 24- and 26-carbons. It is expressed in liver and associated with endoplasmic reticulum but not with peroxisomes. Its primary role is in fatty acid elongation or complex lipid synthesis rather than in degradation. This gene has a mouse ortholog. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:65918286-65927713
Strand Reverse strand
Band
Transcripts
ENSBTAT00000020170 ENSBTAP00000020170
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0015245 fatty acid transporter activity
GO:0031957 very long-chain fatty acid-CoA ligase activity
Biological Process
GO:0000038 very long-chain fatty acid metabolic process
GO:0006642 triglyceride mobilization
GO:0006699 bile acid biosynthetic process
GO:0008152 metabolic process
GO:0008206 bile acid metabolic process
GO:0015908 fatty acid transport
GO:0015911 plasma membrane long-chain fatty acid transport
GO:0046951 ketone body biosynthetic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0009925 basal plasma membrane
GO:0030176 integral component of endoplasmic reticulum membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Synthesis of bile acids and bile salts via 24-hydroxycholesterol pathway
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol pathway
Synthesis of bile acids and bile salts pathway
Recycling of bile acids and salts pathway
Metabolism of lipids and lipoproteins pathway
Bile acid and bile salt metabolism pathway
Metabolism pathway
Recycling of bile acids and salts pathway
Synthesis of bile acids and bile salts via 24-hydroxycholesterol pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Synthesis of bile acids and bile salts pathway
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol pathway
Bile acid and bile salt metabolism pathway
KEGG
PPAR signaling pathway pathway
Primary bile acid biosynthesis pathway
Bile secretion pathway
Primary bile acid biosynthesis pathway
PPAR signaling pathway pathway
Bile secretion pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MX08
UniProt Splice Variant
Entrez Gene 533016
UniGene Bt.21212
RefSeq NM_001103273
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02047916 DAAA02047917
GenPept
RNA Seq Atlas 533016