Version 5.4
Bos taurus Gene: PLXNB2
Summary
InnateDB Gene IDBG-642544.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLXNB2
Gene Name plexin-B2 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000014966
Encoded Proteins
IDBP-695106
plexin B2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196576:
Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that participate in axon guidance and cell migration in response to semaphorins (Perrot et al. (2002) [PubMed 12183458]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:119840726-119854120
Strand Reverse strand
Band
Transcripts
ENSBTAT00000019923 ENSBTAP00000019923
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
GO:0017154 semaphorin receptor activity
Biological Process
GO:0001843 neural tube closure
GO:0001932 regulation of protein phosphorylation
GO:0007165 signal transduction
GO:0007275 multicellular organismal development
GO:0007405 neuroblast proliferation
GO:0007420 brain development
GO:0008360 regulation of cell shape
GO:0032319 regulation of Rho GTPase activity
GO:0050772 positive regulation of axonogenesis
GO:0071526 semaphorin-plexin signaling pathway
GO:2001222 regulation of neuron migration
Cellular Component
GO:0005622 intracellular
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000196576
View Gene Order
ENSMUSG00000036606
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04360
Axon guidance pathway
mmu04360
Axon guidance pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.3323
RefSeq NM_001205629 XM_005207504 XM_005207505 XM_005207506
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca