Version 5.4
Bos taurus Gene: STAT1
Summary
InnateDB Gene IDBG-642654.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STAT1
Gene Name signal transducer and activator of transcription 1-alpha/beta
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000007867
Encoded Proteins
IDBP-695242
signal transducer and activator of transcription 1-alpha/beta
IDBP-695255
signal transducer and activator of transcription 1-alpha/beta
IDBP-695258
signal transducer and activator of transcription 1-alpha/beta
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:79888206-79973705
Strand Reverse strand
Band
Transcripts
ENSBTAT00000061553 ENSBTAP00000053390
ENSBTAT00000010351 ENSBTAP00000010351
ENSBTAT00000030584 ENSBTAP00000030561
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding
GO:0000983 RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0004871 signal transducer activity
GO:0005164 tumor necrosis factor receptor binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0019899 enzyme binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0001937 negative regulation of endothelial cell proliferation
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007165 signal transduction
GO:0007259 JAK-STAT cascade
GO:0007584 response to nutrient
GO:0008015 blood circulation
GO:0008284 positive regulation of cell proliferation
GO:0009617 response to bacterium
GO:0016525 negative regulation of angiogenesis
GO:0019221 cytokine-mediated signaling pathway
GO:0031663 lipopolysaccharide-mediated signaling pathway
GO:0032496 response to lipopolysaccharide
GO:0032869 cellular response to insulin stimulus
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0034097 response to cytokine
GO:0034240 negative regulation of macrophage fusion
GO:0035458 cellular response to interferon-beta
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043330 response to exogenous dsRNA
GO:0043434 response to peptide hormone
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0051591 response to cAMP
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0061326 renal tubule development
GO:0072136 metanephric mesenchymal cell proliferation involved in metanephros development
GO:0072162 metanephric mesenchymal cell differentiation
GO:0072308 negative regulation of metanephric nephron tubule epithelial cell differentiation
Cellular Component
GO:0000790 nuclear chromatin
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.103666 Bt.107066 Bt.33292
RefSeq NM_001077900 NM_001083692 XM_005202570 XM_005202571 XM_005202573 XM_005202574 XM_005202575 XM_005202576 XM_005202577 XM_005202578
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca