InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.38355

Summary

InnateDB Gene

IDBG-642742.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.38355

Gene Name

serine/arginine-rich splicing factor 6

Synonyms

SFRS6

Species

Bos taurus

Ensembl Gene

ENSBTAG00000008527

Encoded Proteins

IDBP-695235

splicing factor, arginine/serine-rich 6

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124193:
The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. Alternative splicing results in multiple transcript variants. In addition, two pseudogenes, one on chromosome 17 and the other on the X chromosome, have been found for this gene.[provided by RefSeq, Sep 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 13:72804660-72810323

Strand

Forward strand

Band

Transcripts

ENSBTAT00000011240

ENSBTAP00000011240

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.

Predicted by orthology
Total	27 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0036002	pre-mRNA binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000380	alternative mRNA splicing, via spliceosome
GO:0000381	regulation of alternative mRNA splicing, via spliceosome
GO:0006376	mRNA splice site selection
GO:0010837	regulation of keratinocyte proliferation
GO:0045617	negative regulation of keratinocyte differentiation
GO:0048025	negative regulation of mRNA splicing, via spliceosome
GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis
GO:0060548	negative regulation of cell death
GO:0061041	regulation of wound healing