Bos taurus Gene: PIGT
Summary
InnateDB Gene IDBG-642899.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PIGT
Gene Name GPI transamidase component PIG-T precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016122
Encoded Proteins
phosphatidylinositol glycan anchor biosynthesis, class T
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124155:
This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:74468626-74480363
Strand Forward strand
Band
Transcripts
ENSBTAT00000021457 ENSBTAP00000021457
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003923 GPI-anchor transamidase activity
GO:0005515 protein binding
Biological Process
GO:0016255 attachment of GPI anchor to protein
GO:0030182 neuron differentiation
GO:0051402 neuron apoptotic process
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0042765 GPI-anchor transamidase complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Attachment of GPI anchor to uPAR pathway
Post-translational modification: synthesis of GPI-anchored proteins pathway
Post-translational protein modification pathway
Metabolism of proteins pathway
Post-translational modification: synthesis of GPI-anchored proteins pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Attachment of GPI anchor to uPAR pathway
KEGG
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.39724
RefSeq NM_001192996 XM_005214532
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas