InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: NPFFR2

Summary

InnateDB Gene

IDBG-642970.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NPFFR2

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000009070

Encoded Proteins

IDBP-695481

neuropeptide FF receptor 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000056291:
This gene encodes a member of a subfamily of G-protein-coupled neuropeptide receptors. This protein is activated by the neuropeptides A-18-amide (NPAF) and F-8-amide (NPFF) and may function in pain modulation and regulation of the opioid system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 6:89052210-89059348

Strand

Forward strand

Band

Transcripts

ENSBTAT00000011957

ENSBTAP00000011957

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0004930	G-protein coupled receptor activity
GO:0008188	neuropeptide receptor activity
GO:0031628	opioid receptor binding

Biological Process

GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007218	neuropeptide signaling pathway
GO:0043408	regulation of MAPK cascade
GO:0045761	regulation of adenylate cyclase activity
GO:2000479	regulation of cAMP-dependent protein kinase activity