Version 5.4
| Mus musculus Gene: Npffr2 | |||||||||||
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| Summary | |||||||||||
| InnateDB Gene | IDBG-177913.6 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | Npffr2 | ||||||||||
| Gene Name | neuropeptide FF receptor 2 | ||||||||||
| Synonyms | Gpr74; HG31; NPFF2 | ||||||||||
| Species | Mus musculus | ||||||||||
| Ensembl Gene | ENSMUSG00000035528 | ||||||||||
| Encoded Proteins |
neuropeptide FF receptor 2
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| Protein Structure | |||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| Entrez Gene | |||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000056291:
This gene encodes a member of a subfamily of G-protein-coupled neuropeptide receptors. This protein is activated by the neuropeptides A-18-amide (NPAF) and F-8-amide (NPFF) and may function in pain modulation and regulation of the opioid system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009] |
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| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome 5:89527429-89583740 | ||||||||||
| Strand | Forward strand | ||||||||||
| Band | E1 | ||||||||||
| Transcripts |
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| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
GPCR downstream signaling pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Orexin and neuropeptides FF and QRFP bind to their respective receptors pathway
GPCR ligand binding pathway
Peptide ligand-binding receptors pathway
G alpha (q) signalling events pathway
Signal Transduction pathway
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| KEGG |
Neuroactive ligand-receptor interaction pathway
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| INOH | |||||||||||
| PID NCI | |||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Orexin and neuropeptides FF and QRFP bind to their respective receptors pathway
Peptide ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
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| KEGG |
Neuroactive ligand-receptor interaction pathway
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| INOH | |||||||||||
| PID NCI | |||||||||||
| Cross-References | |||||||||||
| SwissProt | |||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | |||||||||||
| UniGene | Mm.447881 | ||||||||||
| RefSeq | NM_133192 XM_006534695 XM_006534696 | ||||||||||
| OMIM | |||||||||||
| CCDS | CCDS19408 | ||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| MGI ID | |||||||||||
| MGI Symbol | |||||||||||
| EMBL | |||||||||||
| GenPept | |||||||||||
| RNA Seq Atlas | |||||||||||