InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: MGC159964

Summary

InnateDB Gene

IDBG-643702.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MGC159964

Gene Name

WD repeat domain phosphoinositide-interacting protein 1

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000039556

Encoded Proteins

IDBP-696281

WD repeat domain phosphoinositide-interacting protein 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000070540:
WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI1, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM, Mar 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:62424507-62457703

Strand

Forward strand

Band

Transcripts

ENSBTAT00000054838

ENSBTAP00000050288

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005515	protein binding
GO:0030331	estrogen receptor binding
GO:0032266	phosphatidylinositol-3-phosphate binding
GO:0050681	androgen receptor binding
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding

Biological Process

GO:0006914	autophagy
GO:0048203	vesicle targeting, trans-Golgi to endosome

Cellular Component

GO:0000407	pre-autophagosomal structure
GO:0000421	autophagic vacuole membrane
GO:0005737	cytoplasm
GO:0005802	trans-Golgi network
GO:0010008	endosome membrane
GO:0034045	pre-autophagosomal structure membrane