Version 5.4
Bos taurus Gene: TNP1
Summary
InnateDB Gene IDBG-643744.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TNP1
Gene Name Spermatid nuclear transition protein 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000019003
Encoded Proteins
IDBP-696320
Spermatid nuclear transition protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000118245:
Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1, MIM 182880; PRM2, MIM 182890) (Luerssen et al., 1990 [PubMed 2249851]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:105576568-105577158
Strand Reverse strand
Band
Transcripts
ENSBTAT00000025292 ENSBTAP00000025292
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
GO:0000012 single strand break repair
GO:0006337 nucleosome disassembly
GO:0006338 chromatin remodeling
GO:0006342 chromatin silencing
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0007286 spermatid development
GO:0007290 spermatid nucleus elongation
GO:0019953 sexual reproduction
GO:0030154 cell differentiation
GO:0030317 sperm motility
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000118245
View Gene Order
ENSMUSG00000026182
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_174199
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca