InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: AQP4

Summary

InnateDB Gene

IDBG-643803.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AQP4

Gene Name

Aquaporin-4

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000019037

Encoded Proteins

IDBP-696393

Aquaporin-4

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171885:
This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The encoded protein is the predominant aquaporin found in brain. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 24:30362738-30377272

Strand

Forward strand

Band

Transcripts

ENSBTAT00000025341

ENSBTAP00000025341

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0015250	water channel activity

Biological Process

GO:0006810	transport
GO:0006833	water transport
GO:0007605	sensory perception of sound
GO:0030104	water homeostasis
GO:0050891	multicellular organismal water homeostasis
GO:0070295	renal water absorption
GO:0071346	cellular response to interferon-gamma

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0005911	cell-cell junction
GO:0009897	external side of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016323	basolateral plasma membrane