Bos taurus Gene: SLBP
Summary
InnateDB Gene IDBG-643894.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLBP
Gene Name histone RNA hairpin-binding protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000001328
Encoded Proteins
stem-loop binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163950:
This gene encodes a protein that binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:109613823-109629337
Strand Reverse strand
Band
Transcripts
ENSBTAT00000001753 ENSBTAP00000001753
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
GO:0071207 histone pre-mRNA stem-loop binding
Biological Process
GO:0006398 histone mRNA 3'-end processing
GO:0033260 nuclear cell cycle DNA replication
GO:0051028 mRNA transport
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0030529 ribonucleoprotein complex
GO:0071204 histone pre-mRNA 3'end processing complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs pathway
Transport of the SLBP Dependant Mature mRNA pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
Cleavage of Growing Transcript in the Termination Region pathway
RNA Polymerase II Transcription Termination pathway
RNA Polymerase II Transcription pathway
Transport of Mature Transcript to Cytoplasm pathway
Processing of Capped Intronless Pre-mRNA pathway
Transport of Mature mRNAs Derived from Intronless Transcripts pathway
Gene Expression pathway
Transport of Mature Transcript to Cytoplasm pathway
Processing of Capped Intronless Pre-mRNA pathway
RNA Polymerase II Transcription Termination pathway
Cleavage of Growing Transcript in the Termination Region pathway
Gene Expression pathway
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs pathway
Transport of Mature mRNAs Derived from Intronless Transcripts pathway
Transport of the SLBP Dependant Mature mRNA pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
RNA Polymerase II Transcription pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.11511
RefSeq NM_001045880 XM_005208290
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas