Version 5.4
Bos taurus Gene: BT.75467
Summary
InnateDB Gene IDBG-643937.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.75467
Gene Name WD repeat-containing protein 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013607
Encoded Proteins
IDBP-696538
WD repeat-containing protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000071127:
This gene encodes a protein containing 9 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WD domains are involved in protein-protein interactions. The encoded protein may help induce the disassembly of actin filaments. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:110136880-110178474
Strand Reverse strand
Band
Transcripts
ENSBTAT00000018092 ENSBTAP00000018092
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000071127
View Gene Order
ENSMUSG00000005103
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_11
TCR pathway
REACTOME
REACT_318
Platelet degranulation pathway
REACT_1280
Response to elevated platelet cytosolic Ca2+ pathway
REACT_798
Platelet activation, signaling and aggregation pathway
REACT_604
Hemostasis pathway
REACT_230203
Platelet degranulation pathway
REACT_224553
Hemostasis pathway
REACT_224879
Platelet activation, signaling and aggregation pathway
REACT_206166
Response to elevated platelet cytosolic Ca2+ pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MTP5
UniProt Splice Variant
Entrez Gene 533223
UniGene Bt.59546 Bt.75467
RefSeq NM_001046346
HUGO HGNC:12754
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02018593
GenPept
RNA Seq Atlas 533223

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca