Version 5.4
Bos taurus Gene: SF1
Summary
InnateDB Gene IDBG-643976.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SF1
Gene Name splicing factor 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000001035
Encoded Proteins
IDBP-696577
splicing factor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168066:
This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence and is required for the early stages of spliceosome assembly. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 29:43623210-43636775
Strand Reverse strand
Band
Transcripts
ENSBTAT00000001376 ENSBTAP00000001376
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 66 interaction(s) predicted by orthology.
Predicted by orthology
Total 66 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0008270 zinc ion binding
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0030238 male sex determination
GO:0033327 Leydig cell differentiation
GO:0050810 regulation of steroid biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000168066
View Gene Order
ENSMUSG00000024949
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_2
AndrogenReceptor pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A2VDM7
UniProt Splice Variant
Entrez Gene 541229
UniGene Bt.7991
RefSeq NM_001081614 XM_005227167 XM_005227168 XM_005227169
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC133313 DAAA02063538
GenPept AAI33314
RNA Seq Atlas 541229

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca