Version 5.4
Mus musculus Gene: Sf1
Summary
InnateDB Gene IDBG-136142.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sf1
Gene Name splicing factor 1
Synonyms BBP; MZFM; WBP4; Zfp162
Species Mus musculus
Ensembl Gene ENSMUSG00000024949
Encoded Proteins
IDBP-253761
splicing factor 1
IDBP-253763
splicing factor 1
IDBP-253765
splicing factor 1
IDBP-253767
splicing factor 1
IDBP-538818
splicing factor 1
IDBP-534480
splicing factor 1
IDBP-534820
splicing factor 1
IDBP-540788
splicing factor 1
IDBP-539581
splicing factor 1
IDBP-534724
splicing factor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168066:
This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence and is required for the early stages of spliceosome assembly. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:6363690-6378030
Strand Forward strand
Band A
Transcripts
ENSMUST00000113489 ENSMUSP00000109117
ENSMUST00000113488 ENSMUSP00000109116
ENSMUST00000113487 ENSMUSP00000109115
ENSMUST00000113485 ENSMUSP00000109113
ENSMUST00000131252 ENSMUSP00000121309
ENSMUST00000131083
ENSMUST00000146298
ENSMUST00000144409 ENSMUSP00000123175
ENSMUST00000155973 ENSMUSP00000114438
ENSMUST00000154260
ENSMUST00000144239
ENSMUST00000131677
ENSMUST00000125516 ENSMUSP00000117172
ENSMUST00000124667 ENSMUSP00000114788
ENSMUST00000162237 ENSMUSP00000124590
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
They are also associated with 62 interaction(s) predicted by orthology.
Experimentally validated
Total 25 [view]
Protein-Protein 24 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 62 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0008270 zinc ion binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0030238 male sex determination
GO:0033327 Leydig cell differentiation
GO:0048662 negative regulation of smooth muscle cell proliferation
GO:0050810 regulation of steroid biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000168066
View Gene Order
ENSBTAG00000001035
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_2
AndrogenReceptor pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.256422 Mm.408360
RefSeq NM_001110791 NM_011750 XM_006531736 XM_006531737 XM_006531738 XM_006531739 XM_006531740
OMIM
CCDS CCDS50368 CCDS50369
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca