Version 5.4
Bos taurus Gene: BT.23217
Summary
InnateDB Gene IDBG-644025.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.23217
Gene Name phosphoglycerate mutase 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000014547
Encoded Proteins
IDBP-696628
phosphoglycerate mutase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164708:
Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). This gene encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X. [provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:370972-373326
Strand Reverse strand
Band
Transcripts
ENSBTAT00000019336 ENSBTAP00000019336
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004619 phosphoglycerate mutase activity
GO:0005515 protein binding
GO:0016853 isomerase activity
GO:0016868 intramolecular transferase activity, phosphotransferases
Biological Process
GO:0006096 glycolytic process
GO:0006941 striated muscle contraction
GO:0008152 metabolic process
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000164708
View Gene Order
ENSMUSG00000020475
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1383
Glycolysis pathway
REACT_1520
Gluconeogenesis pathway
REACT_200783
Myoclonic epilepsy of Lafora pathway
REACT_474
Metabolism of carbohydrates pathway
REACT_111217
Metabolism pathway
REACT_116125
Disease pathway
REACT_723
Glucose metabolism pathway
REACT_200833
Glycogen storage diseases pathway
REACT_189085
Disease pathway
REACT_232322
Glycolysis pathway
REACT_261601
Glucose metabolism pathway
REACT_188937
Metabolism pathway
REACT_263230
Gluconeogenesis pathway
REACT_203949
Glycogen storage diseases pathway
REACT_203841
Myoclonic epilepsy of Lafora pathway
REACT_248571
Metabolism of carbohydrates pathway
KEGG
hsa00010
Glycolysis / Gluconeogenesis pathway
hsa00260
Glycine, serine and threonine metabolism pathway
mmu00010
Glycolysis / Gluconeogenesis pathway
mmu00260
Glycine, serine and threonine metabolism pathway
INOH
INOH website
Glycolysis Gluconeogenesis pathway
PID NCI
Cross-References
SwissProt
TrEMBL F1N2F2
UniProt Splice Variant
Entrez Gene 515067
UniGene Bt.23217
RefSeq NM_001038111
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02053419
GenPept
RNA Seq Atlas 515067

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca