Version 5.4
| Bos taurus Gene: BANF1 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-644332.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | BANF1 | ||||||||
| Gene Name | Barrier-to-autointegration factor | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000031875 | ||||||||
| Encoded Proteins |
Barrier-to-autointegration factor
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000175334:
The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Jan 2009] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 29:44759486-44761429 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 49 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
M Phase pathway
Mitotic Metaphase and Anaphase pathway
Mitotic Anaphase pathway
Nuclear Envelope Breakdown pathway
Clearance of Nuclear Envelope Membranes from Chromatin pathway
Cell Cycle, Mitotic pathway
Initiation of Nuclear Envelope Reformation pathway
Cell Cycle pathway
Nuclear Envelope Reassembly pathway
Mitotic Prophase pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Clearance of Nuclear Envelope Membranes from Chromatin pathway
Initiation of Nuclear Envelope Reformation pathway
APOBEC3G mediated resistance to HIV-1 infection pathway
Vpr-mediated nuclear import of PICs pathway
2-LTR circle formation pathway
Autointegration results in viral DNA circles pathway
Integration of provirus pathway
Early Phase of HIV Life Cycle pathway
Interactions of Vpr with host cellular proteins pathway
Cell Cycle pathway
M Phase pathway
HIV Life Cycle pathway
Mitotic Anaphase pathway
Mitotic Prophase pathway
Nuclear Envelope Reassembly pathway
Cell Cycle, Mitotic pathway
HIV Infection pathway
Host Interactions of HIV factors pathway
Integration of viral DNA into host genomic DNA pathway
Nuclear Envelope Breakdown pathway
Disease pathway
Mitotic Metaphase and Anaphase pathway
Nuclear Envelope Breakdown pathway
Cell Cycle, Mitotic pathway
Nuclear Envelope Reassembly pathway
Cell Cycle pathway
M Phase pathway
Mitotic Metaphase and Anaphase pathway
Initiation of Nuclear Envelope Reformation pathway
Mitotic Prophase pathway
Mitotic Anaphase pathway
Clearance of Nuclear Envelope Membranes from Chromatin pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | |||||||||
| UniGene | |||||||||
| RefSeq | NM_182988 XM_001787208 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | |||||||||
| GenPept | |||||||||
| RNA Seq Atlas | |||||||||