Version 5.4
Bos taurus Gene: NFIC
Summary
InnateDB Gene IDBG-644427.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NFIC
Gene Name nuclear factor 1 C-type
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000008520
Encoded Proteins
IDBP-697064
nuclear factor 1 C-type
IDBP-697066
nuclear factor 1 C-type
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000141905:
The protein encoded by this gene belongs to the CTF/NF-I family. These are dimeric DNA-binding proteins, and function as cellular transcription factors and as replication factors for adenovirus DNA replication. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:21676708-21748618
Strand Reverse strand
Band
Transcripts
ENSBTAT00000023727 ENSBTAP00000023727
ENSBTAT00000039403 ENSBTAP00000039197
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006260 DNA replication
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0042475 odontogenesis of dentin-containing tooth
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0005730 nucleolus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000141905
View Gene Order
ENSMUSG00000055053
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22339
RNA Polymerase III Abortive And Retractive Initiation pathway
REACT_63
RNA Polymerase III Transcription Termination pathway
REACT_1371
RNA Polymerase III Transcription pathway
REACT_21352
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_71
Gene Expression pathway
REACT_244415
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_261233
RNA Polymerase III Abortive And Retractive Initiation pathway
REACT_233572
Gene Expression pathway
REACT_221403
RNA Polymerase III Transcription Termination pathway
REACT_237241
RNA Polymerase III Transcription pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q4ZJ65
UniProt Splice Variant
Entrez Gene 553098
UniGene Bt.39651
RefSeq NM_001024574
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02019642 DAAA02019643 DAAA02019644 DAAA02019645 DAAA02019646 DAAA02019647 DAAA02019648 DAAA02019649 DAAA02019650 DAAA02019651 DAAA02019652 DAAA02019653 DQ004950
GenPept AAY24696
RNA Seq Atlas 553098

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca