Bos taurus Gene: BT.47646
Summary
InnateDB Gene IDBG-644613.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.47646
Gene Name hydroxyacid-oxoacid transhydrogenase, mitochondrial precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004476
Encoded Proteins
hydroxyacid-oxoacid transhydrogenase, mitochondrial precursor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147576:
The ADHFE1 gene encodes hydroxyacid-oxoacid transhydrogenase (EC 1.1.99.24), which is responsible for the oxidation of 4-hydroxybutyrate in mammalian tissues (Kardon et al., 2006 [PubMed 16616524]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:32702918-32735889
Strand Forward strand
Band
Transcripts
ENSBTAT00000005874 ENSBTAP00000005874
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0047988 hydroxyacid-oxoacid transhydrogenase activity
Biological Process
GO:0015993 molecular hydrogen transport
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate pathway
Pyruvate metabolism and Citric Acid (TCA) cycle pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Metabolism pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Metabolism pathway
Pyruvate metabolism and Citric Acid (TCA) cycle pathway
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate pathway
KEGG
INOH
Tyrosine metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL F1MAZ7
UniProt Splice Variant
Entrez Gene 507711
UniGene Bt.47646
RefSeq NM_001101887
HUGO HGNC:16354
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02038676
GenPept
RNA Seq Atlas 507711