Version 5.4
Bos taurus Gene: AP3D1
Summary
InnateDB Gene IDBG-644616.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AP3D1
Gene Name AP-3 complex subunit delta-1
Synonyms BLVR
Species Bos taurus
Ensembl Gene ENSBTAG00000009034
Encoded Proteins
IDBP-697281
AP-3 complex subunit delta-1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000065000:
The protein encoded by this gene is a subunit of the AP3 adaptor-like complex, which is not clathrin-associated, but is associated with the golgi region, as well as more peripheral structures. The AP-3 complex facilitates the budding of vesicles from the golgi membrane, and may be directly involved in trafficking to lysosomes. This subunit is implicated in intracellular biogenesis and trafficking of pigment granules, and possibly platelet dense granules and neurotransmitter vesicles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:22709434-22743787
Strand Forward strand
Band
Transcripts
ENSBTAT00000011906 ENSBTAP00000011906
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0008565 protein transporter activity
Biological Process
GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0008089 anterograde axon cargo transport
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0019882 antigen processing and presentation
GO:0033365 protein localization to organelle
GO:0035646 endosome to melanosome transport
GO:0048007 antigen processing and presentation, exogenous lipid antigen via MHC class Ib
GO:0048490 anterograde synaptic vesicle transport
GO:0048499 synaptic vesicle membrane organization
GO:0051138 positive regulation of NK T cell differentiation
GO:0061088 regulation of sequestering of zinc ion
GO:0072657 protein localization to membrane
Cellular Component
GO:0000139 Golgi membrane
GO:0005737 cytoplasm
GO:0005765 lysosomal membrane
GO:0005794 Golgi apparatus
GO:0010008 endosome membrane
GO:0016020 membrane
GO:0030117 membrane coat
GO:0030424 axon
GO:0043195 terminal bouton
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000065000
View Gene Order
ENSMUSG00000020198
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04142
Lysosome pathway
mmu04142
Lysosome pathway
INOH
PID NCI
Cross-References
SwissProt Q865S1
TrEMBL
UniProt Splice Variant
Entrez Gene 281023
UniGene Bt.8223
RefSeq NM_173998 XM_005209027
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AB015979 M98430 S75828
GenPept AAA30633 AAB32770 BAA36591
RNA Seq Atlas 281023

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca