Bos taurus Gene: TAF12
Summary
InnateDB Gene IDBG-644868.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TAF12
Gene Name Transcription initiation factor TFIID subunit 12
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000026660
Encoded Proteins
Transcription initiation factor TFIID subunit 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000120656:
Control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TAF proteins. Different TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. TAF12 interacts directly with TBP as well as with TAF2I. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:125394311-125418237
Strand Forward strand
Band
Transcripts
ENSBTAT00000037998 ENSBTAP00000037817
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0043565 sequence-specific DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006352 DNA-templated transcription, initiation
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005669 transcription factor TFIID complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
RNA Polymerase II Transcription pathway
RNA Polymerase II Pre-transcription Events pathway
RNA Polymerase II Promoter Escape pathway
Gene Expression pathway
Chromatin organization pathway
HATs acetylate histones pathway
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
RNA Polymerase II Transcription Initiation pathway
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
RNA Polymerase II Pre-transcription Events pathway
RNA Polymerase II Promoter Escape pathway
RNA Polymerase II Transcription Initiation pathway
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
HIV Transcription Initiation pathway
RNA Polymerase II HIV Promoter Escape pathway
Transcription of the HIV genome pathway
Late Phase of HIV Life Cycle pathway
HATs acetylate histones pathway
RNA Polymerase II Transcription pathway
HIV Life Cycle pathway
Chromatin organization pathway
Chromatin modifying enzymes pathway
HIV Infection pathway
Gene Expression pathway
Disease pathway
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
Chromatin organization pathway
RNA Polymerase II Transcription Initiation pathway
RNA Polymerase II Promoter Escape pathway
HATs acetylate histones pathway
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
Chromatin modifying enzymes pathway
RNA Polymerase II Pre-transcription Events pathway
Gene Expression pathway
RNA Polymerase II Transcription pathway
KEGG
Basal transcription factors pathway
Basal transcription factors pathway
INOH
PID NCI
Validated targets of C-MYC transcriptional activation
C-MYC pathway
Cross-References
SwissProt Q3T174
TrEMBL
UniProt Splice Variant
Entrez Gene 614227
UniGene
RefSeq NM_001034754 XM_005203230 XM_005203231 XM_005203232 XM_005203233 XM_005203234 XM_005203235
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102082
GenPept AAI02083
RNA Seq Atlas 614227