Version 5.4
Bos taurus Gene: SEMA6A
Summary
InnateDB Gene IDBG-645045.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEMA6A
Gene Name semaphorin-6A precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000020489
Encoded Proteins
IDBP-697728
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000092421:
The transmembrane semaphorin SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection (Leighton et al., 2001 [PubMed 11242070]).[supplied by OMIM, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:38732390-38795851
Strand Forward strand
Band
Transcripts
ENSBTAT00000043906 ENSBTAP00000041442
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0004888 transmembrane signaling receptor activity
GO:0005515 protein binding
GO:0030215 semaphorin receptor binding
Biological Process
GO:0001764 neuron migration
GO:0007166 cell surface receptor signaling pathway
GO:0007275 multicellular organismal development
GO:0051642 centrosome localization
GO:0071526 semaphorin-plexin signaling pathway
GO:2001224 positive regulation of neuron migration
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000092421
View Gene Order
ENSMUSG00000019647
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19200
Other semaphorin interactions pathway
REACT_111045
Developmental Biology pathway
REACT_19271
Semaphorin interactions pathway
REACT_18266
Axon guidance pathway
REACT_261444
Axon guidance pathway
REACT_188576
Developmental Biology pathway
REACT_263034
Semaphorin interactions pathway
REACT_231928
Other semaphorin interactions pathway
KEGG
hsa04360
Axon guidance pathway
mmu04360
Axon guidance pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.53457
RefSeq NM_001193209 XM_005209139
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca