Bos taurus Gene: DHDDS
Summary
InnateDB Gene IDBG-645130.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DHDDS
Gene Name dehydrodolichyl diphosphate synthase isoform a
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000003235
Encoded Proteins
dehydrodolichyl diphosphate synthase isoform a
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000117682:
The protein encoded by this gene catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier lipid required for the biosynthesis of several classes of glycoproteins. Mutations in this gene are associated with retinitis pigmentosa type 59. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:127266788-127295155
Strand Reverse strand
Band
Transcripts
ENSBTAT00000010328 ENSBTAP00000010328
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
Biological Process
GO:0008152 metabolic process
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Synthesis of Dolichyl-phosphate pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Asparagine N-linked glycosylation pathway
Post-translational protein modification pathway
Synthesis of substrates in N-glycan biosythesis pathway
Metabolism of proteins pathway
Synthesis of substrates in N-glycan biosythesis pathway
Synthesis of Dolichyl-phosphate pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Asparagine N-linked glycosylation pathway
KEGG
Terpenoid backbone biosynthesis pathway
Terpenoid backbone biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q58DN9
UniProt Splice Variant
Entrez Gene 523264
UniGene Bt.87215
RefSeq NM_001035346
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BT021558 DAAA02006373
GenPept AAX46405
RNA Seq Atlas 523264