Version 5.4
Bos taurus Gene: POP1
Summary
InnateDB Gene IDBG-645172.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POP1
Gene Name ribonucleases P/MRP protein subunit POP1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000012596
Encoded Proteins
IDBP-697856
processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104356:
This gene encodes the protein subunit of two different small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is a ribonuclease that localizes to the nucleus and functions in pre-RNA processing. This protein is also an autoantigen in patients suffering from connective tissue diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:68377530-68406373
Strand Reverse strand
Band
Transcripts
ENSBTAT00000016721 ENSBTAP00000016721
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000171 ribonuclease MRP activity
GO:0004526 ribonuclease P activity
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0001682 tRNA 5'-leader removal
GO:0006396 RNA processing
GO:0016078 tRNA catabolic process
GO:0090501 RNA phosphodiester bond hydrolysis
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic
Cellular Component
GO:0000172 ribonuclease MRP complex
GO:0005615 extracellular space
GO:0005655 nucleolar ribonuclease P complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000104356
View Gene Order
ENSMUSG00000022325
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03013
RNA transport pathway
mmu03013
RNA transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BF14
UniProt Splice Variant
Entrez Gene 511306
UniGene Bt.60695
RefSeq NM_001193215 XM_005215620
HUGO HGNC:30129
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02039411
GenPept
RNA Seq Atlas 511306

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca