Version 5.4
| Bos taurus Gene: MGAT1 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-645360.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | MGAT1 | ||||||||
| Gene Name | alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | ||||||||
| Synonyms | GNT-1 | ||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000001546 | ||||||||
| Encoded Proteins |
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131446:
There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 7:41337278-41354610 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
N-glycan trimming and elongation in the cis-Golgi pathway
Transport to the Golgi and subsequent modification pathway
Asparagine N-linked glycosylation pathway
Post-translational protein modification pathway
Metabolism of proteins pathway
Transport to the Golgi and subsequent modification pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Asparagine N-linked glycosylation pathway
N-glycan trimming and elongation in the cis-Golgi pathway
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| KEGG |
N-Glycan biosynthesis pathway
N-Glycan biosynthesis pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | Q58CX8 Q5E9I4 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 534248 | ||||||||
| UniGene | Bt.100111 Bt.103211 Bt.8583 | ||||||||
| RefSeq | XM_005199031 XM_005209207 NM_001015653 XM_005199030 XM_005209206 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC151367 BT020936 BT021819 DAAA02020072 DAAA02020073 | ||||||||
| GenPept | AAI51368 AAX08953 AAX46666 | ||||||||
| RNA Seq Atlas | 101909343 534248 | ||||||||