Bos taurus Gene: TALDO1
Summary
InnateDB Gene IDBG-645546.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TALDO1
Gene Name transaldolase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000010336
Encoded Proteins
transaldolase
transaldolase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000177156:
Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 29:50856122-50863486
Strand Reverse strand
Band
Transcripts
ENSBTAT00000055244 ENSBTAP00000048861
ENSBTAT00000013650 ENSBTAP00000013650
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity
GO:0016740 transferase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006098 pentose-phosphate shunt
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Pentose phosphate pathway (hexose monophosphate shunt) pathway
Insulin effects increased synthesis of Xylulose-5-Phosphate pathway
Integration of energy metabolism pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
Metabolism pathway
Disease pathway
Glycogen storage diseases pathway
Insulin effects increased synthesis of Xylulose-5-Phosphate pathway
Disease pathway
Integration of energy metabolism pathway
Metabolism pathway
Pentose phosphate pathway (hexose monophosphate shunt) pathway
Glycogen storage diseases pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
KEGG
Pentose phosphate pathway pathway
Pentose phosphate pathway pathway
INOH
Pentose phosphate cycle pathway
PID NCI
Cross-References
SwissProt
TrEMBL G5E5C8 Q58DR3
UniProt Splice Variant
Entrez Gene 513453
UniGene Bt.7283
RefSeq NM_001035283
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BT021534 DAAA02063761
GenPept AAX46381
RNA Seq Atlas 513453