Bos taurus Gene: DDOST | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-645655.3 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | DDOST | ||||||||||
Gene Name | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit | ||||||||||
Synonyms | |||||||||||
Species | Bos taurus | ||||||||||
Ensembl Gene | ENSBTAG00000006085 | ||||||||||
Encoded Proteins |
dolichyl-diphosphooligosaccharide--protein glycosyltransferase
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
Entrez Gene | |||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000244038:
This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 2:132587705-132600729 | ||||||||||
Strand | Forward strand | ||||||||||
Band | |||||||||||
Transcripts |
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Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 39 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
Species
Mus musculus
Homo sapiens
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||
NETPATH | |||||||||||
REACTOME |
Innate Immune System pathway
Translation pathway
Immune System pathway
Metabolism of proteins pathway
Advanced glycosylation endproduct receptor signaling pathway
SRP-dependent cotranslational protein targeting to membrane pathway
Gene Expression pathway
Advanced glycosylation endproduct receptor signaling pathway
Asparagine N-linked glycosylation pathway
SRP-dependent cotranslational protein targeting to membrane pathway
Post-translational protein modification pathway
Innate Immune System pathway
Translation pathway
Metabolism of proteins pathway
Immune System pathway
Gene Expression pathway
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KEGG |
N-Glycan biosynthesis pathway
Protein processing in endoplasmic reticulum pathway
N-Glycan biosynthesis pathway
Protein processing in endoplasmic reticulum pathway
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INOH | |||||||||||
PID NCI | |||||||||||
Cross-References | |||||||||||
SwissProt | |||||||||||
TrEMBL | F1N632 | ||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 510682 | ||||||||||
UniGene | |||||||||||
RefSeq | XM_005203105 | ||||||||||
HUGO | HGNC:2728 | ||||||||||
OMIM | |||||||||||
CCDS | |||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | DAAA02006487 DAAA02006488 DAAA02006489 | ||||||||||
GenPept | |||||||||||
RNA Seq Atlas | 510682 | ||||||||||