Bos taurus Gene: IP6K2
Summary
InnateDB Gene IDBG-646094.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IP6K2
Gene Name inositol hexakisphosphate kinase 2
Synonyms IHPK2
Species Bos taurus
Ensembl Gene ENSBTAG00000021853
Encoded Proteins
inositol hexakisphosphate kinase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000068745:
This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:51747919-51771674
Strand Forward strand
Band
Transcripts
ENSBTAT00000030644 ENSBTAP00000030616
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity
GO:0016301 kinase activity
Biological Process
GO:0016310 phosphorylation
GO:0030308 negative regulation of cell growth
GO:0043065 positive regulation of apoptotic process
GO:0046854 phosphatidylinositol phosphorylation
Cellular Component
GO:0005634 nucleus
GO:0045111 intermediate filament cytoskeleton
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Interferon alpha/beta signaling pathway
Synthesis of IPs in the nucleus pathway
Cytokine Signaling in Immune system pathway
Interferon Signaling pathway
Immune System pathway
Inositol phosphate metabolism pathway
Metabolism pathway
Metabolism pathway
Synthesis of IPs in the nucleus pathway
Inositol phosphate metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.49510
RefSeq NM_001034317
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas