Bos taurus Gene: NCKIPSD | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-646096.3 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | NCKIPSD | ||||||
Gene Name | NCK-interacting protein with SH3 domain | ||||||
Synonyms | |||||||
Species | Bos taurus | ||||||
Ensembl Gene | ENSBTAG00000021850 | ||||||
Encoded Proteins |
NCK interacting protein with SH3 domain
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
Entrez Gene | |||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000213672:
The protein encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 22:51773520-51785996 | ||||||
Strand | Forward strand | ||||||
Band | |||||||
Transcripts |
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Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
Species
Mus musculus
Homo sapiens
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||
NETPATH | |||||||
REACTOME |
Innate Immune System pathway
Regulation of actin dynamics for phagocytic cup formation pathway
Immune System pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Regulation of actin dynamics for phagocytic cup formation pathway
Innate Immune System pathway
Immune System pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
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KEGG | |||||||
INOH | |||||||
PID NCI | |||||||
Cross-References | |||||||
SwissProt | |||||||
TrEMBL | E1BG80 | ||||||
UniProt Splice Variant | |||||||
Entrez Gene | 516941 | ||||||
UniGene | Bt.24482 | ||||||
RefSeq | NM_001191238 XM_005222828 | ||||||
HUGO | HGNC:15486 | ||||||
OMIM | |||||||
CCDS | |||||||
HPRD | |||||||
IMGT | |||||||
EMBL | DAAA02054431 | ||||||
GenPept | |||||||
RNA Seq Atlas | 516941 | ||||||