Bos taurus Gene: SHISA5
Summary
InnateDB Gene IDBG-646132.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SHISA5
Gene Name protein shisa-5 precursor
Synonyms SCOTIN
Species Bos taurus
Ensembl Gene ENSBTAG00000009183
Encoded Proteins
protein shisa-5 precursor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164054:
This gene encodes a member of the shisa family. The encoded protein is localized to the endoplasmic reticulum, and together with p53 induces apoptosis in a caspase-dependent manner. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:51944064-51969644
Strand Forward strand
Band
Transcripts
ENSBTAT00000012101 ENSBTAP00000012101
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0005515 protein binding
GO:0050699 WW domain binding
Biological Process
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
Cellular Component
GO:0005635 nuclear envelope
GO:0005783 endoplasmic reticulum
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
p53 signaling pathway pathway
p53 signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MFP6
UniProt Splice Variant
Entrez Gene 616861
UniGene Bt.2340
RefSeq NM_001035486
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02054431 DAAA02054432
GenPept
RNA Seq Atlas 100335346 616861