Bos taurus Gene: BT.17789
Summary
InnateDB Gene IDBG-646604.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.17789
Gene Name CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase precursor
Synonyms SIAT8D; ST8Sia-IV
Species Bos taurus
Ensembl Gene ENSBTAG00000021445
Encoded Proteins
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113532:
The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:102456175-102555855
Strand Reverse strand
Band
Transcripts
ENSBTAT00000028590 ENSBTAP00000028590
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity
GO:0008373 sialyltransferase activity
GO:0016740 transferase activity
GO:0016757 transferase activity, transferring glycosyl groups
Biological Process
GO:0001574 ganglioside biosynthetic process
GO:0006486 protein glycosylation
GO:0006491 N-glycan processing
GO:0009311 oligosaccharide metabolic process
GO:0097503 sialylation
Cellular Component
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030173 integral component of Golgi membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Asparagine N-linked glycosylation pathway
NCAM1 interactions pathway
NCAM signaling for neurite out-growth pathway
Developmental Biology pathway
Post-translational protein modification pathway
Synthesis of substrates in N-glycan biosythesis pathway
Axon guidance pathway
Sialic acid metabolism pathway
Metabolism of proteins pathway
Synthesis of substrates in N-glycan biosythesis pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
NCAM1 interactions pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Axon guidance pathway
Asparagine N-linked glycosylation pathway
Developmental Biology pathway
NCAM signaling for neurite out-growth pathway
Sialic acid metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MVI9
UniProt Splice Variant
Entrez Gene 407768
UniGene Bt.17789
RefSeq NM_001001163
HUGO HGNC:10871
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02021435 DAAA02021436
GenPept
RNA Seq Atlas 407768