Version 5.4
| Mus musculus Gene: St8sia4 | |||||||||||
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| Summary | |||||||||||
| InnateDB Gene | IDBG-184275.6 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | St8sia4 | ||||||||||
| Gene Name | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 | ||||||||||
| Synonyms | PST; PST-1; SIAT8-D; Siat8d; ST8SiaIV | ||||||||||
| Species | Mus musculus | ||||||||||
| Ensembl Gene | ENSMUSG00000040710 | ||||||||||
| Encoded Proteins |
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| Entrez Gene | |||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113532:
The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome 1:95587682-95667571 | ||||||||||
| Strand | Reverse strand | ||||||||||
| Band | D | ||||||||||
| Transcripts |
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| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
Synthesis of substrates in N-glycan biosythesis pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
NCAM1 interactions pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Axon guidance pathway
Asparagine N-linked glycosylation pathway
Developmental Biology pathway
NCAM signaling for neurite out-growth pathway
Sialic acid metabolism pathway
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| KEGG | |||||||||||
| INOH | |||||||||||
| PID NCI | |||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Asparagine N-linked glycosylation pathway
NCAM1 interactions pathway
NCAM signaling for neurite out-growth pathway
Developmental Biology pathway
Post-translational protein modification pathway
Synthesis of substrates in N-glycan biosythesis pathway
Axon guidance pathway
Sialic acid metabolism pathway
Metabolism of proteins pathway
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| KEGG | |||||||||||
| INOH | |||||||||||
| PID NCI | |||||||||||
| Cross-References | |||||||||||
| SwissProt | Q64692 | ||||||||||
| TrEMBL | Q53WR7 | ||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 20452 | ||||||||||
| UniGene | |||||||||||
| RefSeq | NM_001159745 NM_009183 | ||||||||||
| OMIM | |||||||||||
| CCDS | CCDS15201 | ||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| MGI ID | MGI:106018 | ||||||||||
| MGI Symbol | St8sia4 | ||||||||||
| EMBL | AJ223956 CH466520 X86000 Y09484 Y09485 Y09486 Y09487 Y09488 | ||||||||||
| GenPept | CAA11685 CAA59992 CAA70692 EDL39918 | ||||||||||
| RNA Seq Atlas | 20452 | ||||||||||