Bos taurus Gene: SLC8A3 | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-646813.3 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | SLC8A3 | ||||||||||||
Gene Name | sodium/calcium exchanger 3 precursor | ||||||||||||
Synonyms | |||||||||||||
Species | Bos taurus | ||||||||||||
Ensembl Gene | ENSBTAG00000027080 | ||||||||||||
Encoded Proteins |
solute carrier family 8 (sodium/calcium exchanger), member 3
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100678:
This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described. [provided by RefSeq, Jul 2008] This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described. [provided by RefSeq, Aug 2013] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 10:82128379-82273227 | ||||||||||||
Strand | Reverse strand | ||||||||||||
Band | |||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
Reduction of cytosolic Ca++ levels pathway
Platelet homeostasis pathway
Sodium/Calcium exchangers pathway
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
Transmembrane transport of small molecules pathway
Platelet calcium homeostasis pathway
SLC-mediated transmembrane transport pathway
Hemostasis pathway
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KEGG |
Calcium signaling pathway pathway
Protein digestion and absorption pathway
Calcium signaling pathway pathway
Protein digestion and absorption pathway
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INOH | |||||||||||||
PID NCI | |||||||||||||
Cross-References | |||||||||||||
SwissProt | |||||||||||||
TrEMBL | E1BM32 | ||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 540307 | ||||||||||||
UniGene | Bt.87822 | ||||||||||||
RefSeq | NM_001191199 XM_005212032 XM_005212034 | ||||||||||||
HUGO | HGNC:11070 | ||||||||||||
OMIM | |||||||||||||
CCDS | |||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | DAAA02029516 DAAA02029517 DAAA02029518 DAAA02029519 | ||||||||||||
GenPept | |||||||||||||
RNA Seq Atlas | 540307 | ||||||||||||