Bos taurus Gene: PTGR2
Summary
InnateDB Gene IDBG-646842.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PTGR2
Gene Name Prostaglandin reductase 2
Synonyms ZADH1
Species Bos taurus
Ensembl Gene ENSBTAG00000003747
Encoded Proteins
Prostaglandin reductase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000140043:
This gene encodes an enzyme involved in the metabolism of prostaglandins. The encoded protein catalyzes the NADPH-dependent conversion of 15-keto-prostaglandin E2 to 15-keto-13,14-dihydro-prostaglandin E2. This protein may also be involved in regulating activation of the peroxisome proliferator-activated receptor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:85645803-85666323
Strand Forward strand
Band
Transcripts
ENSBTAT00000004878 ENSBTAP00000004878
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0036132 13-prostaglandin reductase activity
GO:0047522 15-oxoprostaglandin 13-oxidase activity
Biological Process
GO:0006693 prostaglandin metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) pathway
Arachidonic acid metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q32L99
TrEMBL A7E3P5
UniProt Splice Variant
Entrez Gene 506263
UniGene
RefSeq NM_001075249 XM_005211943 XM_005211944 XM_005211945
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC109688 BT030666
GenPept AAI09689 ABS44982
RNA Seq Atlas 506263