Version 5.4
Bos taurus Gene: BT.69917
Summary
InnateDB Gene IDBG-648761.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.69917
Gene Name NTF2-related export protein 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004993
Encoded Proteins
IDBP-701479
NTF2-related export protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000132661:
The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:42398735-42399402
Strand Forward strand
Band
Transcripts
ENSBTAT00000006568 ENSBTAP00000006568
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008536 Ran GTPase binding
Biological Process
GO:0006405 RNA export from nucleus
GO:0006611 protein export from nucleus
GO:0006810 transport
Cellular Component
GO:0005622 intracellular
GO:0005643 nuclear pore
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000132661
View Gene Order
ENSMUSG00000036992
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03013
RNA transport pathway
hsa03015
mRNA surveillance pathway pathway
mmu03013
RNA transport pathway
mmu03015
mRNA surveillance pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MNL5
UniProt Splice Variant
Entrez Gene 520351
UniGene Bt.61944 Bt.69917
RefSeq NM_001075805
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02035858
GenPept
RNA Seq Atlas 520351

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca