InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: MC3R

Summary

InnateDB Gene

IDBG-648794.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MC3R

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000004712

Encoded Proteins

IDBP-701510

Uncharacterized protein

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124089:
This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 13:60185129-60186103

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000006185

ENSBTAP00000006185

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0004930	G-protein coupled receptor activity
GO:0004977	melanocortin receptor activity
GO:0004980	melanocyte-stimulating hormone receptor activity
GO:0005515	protein binding
GO:0042923	neuropeptide binding