Version 5.4
Bos taurus Gene: GJA4
Summary
InnateDB Gene IDBG-648937.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GJA4
Gene Name Gap junction alpha-4 protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013881
Encoded Proteins
IDBP-701642
Gap junction alpha-4 protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000187513:
This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:111481702-111482589
Strand Reverse strand
Band
Transcripts
ENSBTAT00000018428 ENSBTAP00000018428
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001568 blood vessel development
GO:0007154 cell communication
Cellular Component
GO:0005886 plasma membrane
GO:0005921 gap junction
GO:0005922 connexon complex
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000187513
View Gene Order
ENSMUSG00000050234
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_9509
Gap junction assembly pathway
REACT_9411
Gap junction trafficking pathway
REACT_9480
Gap junction trafficking and regulation pathway
REACT_11123
Membrane Trafficking pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt A4IFL1
TrEMBL G1K1Q0
UniProt Splice Variant
Entrez Gene 538913
UniGene Bt.61260
RefSeq NM_001083738
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC134629 DAAA02009223
GenPept AAI34630
RNA Seq Atlas 538913

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca