Mus musculus Gene: Gja4
Summary
InnateDB Gene IDBG-189646.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gja4
Gene Name gap junction protein, alpha 4
Synonyms AU020209; AW558810; Cnx37; Cx37; Gja-4
Species Mus musculus
Ensembl Gene ENSMUSG00000050234
Encoded Proteins
gap junction protein, alpha 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000187513:
This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:127311421-127314039
Strand Reverse strand
Band D2.2
Transcripts
ENSMUST00000053753 ENSMUSP00000062320
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001568 blood vessel development
GO:0003158 endothelium development
GO:0006816 calcium ion transport
GO:0007267 cell-cell signaling
GO:0048265 response to pain
Cellular Component
GO:0005921 gap junction
GO:0005922 connexon complex
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Gap junction assembly pathway
Gap junction trafficking pathway
Gap junction trafficking and regulation pathway
Membrane Trafficking pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt P28235
TrEMBL Q3UPZ2 Q9JIN0
UniProt Splice Variant
Entrez Gene 14612
UniGene Mm.24615
RefSeq NM_008120
OMIM
CCDS CCDS18667
HPRD
IMGT
MGI ID MGI:95715
MGI Symbol Gja4
EMBL AF216831 AF216832 AK143024 CH466552 X57971
GenPept AAF91221 AAF91222 BAE25252 CAA41037 EDL30255
RNA Seq Atlas 14612