InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: NEUROG3

Summary

InnateDB Gene

IDBG-648964.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NEUROG3

Gene Name

Uncharacterized protein

Synonyms

Ngn3

Species

Bos taurus

Ensembl Gene

ENSBTAG00000006431

Encoded Proteins

IDBP-701662

neurogenin 3

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000122859:
The protein encoded by this gene is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4).[provided by RefSeq, May 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 28:26063128-26063775

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000008432

ENSBTAP00000008432

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001047	core promoter binding
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003713	transcription coactivator activity
GO:0031490	chromatin DNA binding
GO:0046983	protein dimerization activity

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0007275	multicellular organismal development
GO:0030855	epithelial cell differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048814	regulation of dendrite morphogenesis
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060290	transdifferentiation