InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: GNA13

Summary

InnateDB Gene

IDBG-64978.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GNA13

Gene Name

guanine nucleotide binding protein (G protein), alpha 13

Synonyms

G13

Species

Homo sapiens

Ensembl Gene

ENSG00000120063

Encoded Proteins

IDBP-383509

guanine nucleotide binding protein (G protein), alpha 13

IDBP-593246

guanine nucleotide binding protein (G protein), alpha 13

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 17:65010715-65056839

Strand

Reverse strand

Band

q24.1

Transcripts

ENST00000439174	ENSP00000400717
ENST00000541118	ENSP00000439647

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	41 [view]
Protein-Protein	38 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	2 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0004871	signal transducer activity
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0019001	guanyl nucleotide binding
GO:0031683	G-protein beta/gamma-subunit complex binding
GO:0031702	type 1 angiotensin receptor binding
GO:0031752	D5 dopamine receptor binding
GO:0046872	metal ion binding

Biological Process

GO:0001525	angiogenesis
GO:0001569	patterning of blood vessels
GO:0001701	in utero embryonic development
GO:0006184	GTP catabolic process
GO:0006928	cellular component movement
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007204	positive regulation of cytosolic calcium ion concentration
GO:0007266	Rho protein signal transduction
GO:0007596	blood coagulation
GO:0008360	regulation of cell shape
GO:0030154	cell differentiation
GO:0030168	platelet activation
GO:0030334	regulation of cell migration
GO:0031584	activation of phospholipase D activity
GO:0035556	intracellular signal transduction

Cellular Component

GO:0005634	nucleus
GO:0005834	heterotrimeric G-protein complex
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0031526	brush border membrane
GO:0042470	melanosome
GO:0070062	extracellular vesicular exosome