Version 5.4
Homo sapiens Gene: SFSWAP
Summary
InnateDB Gene IDBG-64984.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SFSWAP
Gene Name splicing factor, suppressor of white-apricot homolog (Drosophila)
Synonyms SFRS8; SWAP
Species Homo sapiens
Ensembl Gene ENSG00000061936
Encoded Proteins
IDBP-64986
splicing factor, suppressor of white-apricot homolog (Drosophila)
IDBP-589960
splicing factor, suppressor of white-apricot homolog (Drosophila)
IDBP-598395
splicing factor, suppressor of white-apricot homolog (Drosophila)
IDBP-586942
splicing factor, suppressor of white-apricot homolog (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a human homolog of Drosophila splicing regulatory protein. This gene autoregulates its expression by control of splicing of its first two introns. In addition, it also regulates the splicing of fibronectin and CD45 genes. Two transcript variants encoding different isoforms have been identified. [provided by RefSeq, May 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:131711081-131799737
Strand Forward strand
Band q24.33
Transcripts
ENST00000261674 ENSP00000261674
ENST00000540469
ENST00000538548 ENSP00000445832
ENST00000535399
ENST00000535236
ENST00000541286 ENSP00000437738
ENST00000542813
ENST00000535202
ENST00000537164 ENSP00000439957
ENST00000539506
ENST00000537582
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 3 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006376 mRNA splice site selection
GO:0006396 RNA processing
GO:0006397 mRNA processing
GO:0048025 negative regulation of mRNA splicing, via spliceosome
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029439
View Gene Order
ENSBTAG00000000439
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001261411 NM_004592
HUGO
OMIM
CCDS CCDS58290 CCDS9273
HPRD 09055
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca