Homo sapiens Gene: ZNF268
Summary
InnateDB Gene IDBG-66258.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF268
Gene Name zinc finger protein 268
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000090612
Encoded Proteins
IDBP-66281
zinc finger protein 268
IDBP-385363
zinc finger protein 268
IDBP-717826
IDBP-603261
zinc finger protein 268
IDBP-600493
zinc finger protein 268
IDBP-595447
zinc finger protein 268
IDBP-588764
zinc finger protein 268
IDBP-595462
zinc finger protein 268
IDBP-716635
IDBP-589502
zinc finger protein 268
IDBP-602017
zinc finger protein 268
IDBP-586280
zinc finger protein 268
IDBP-717484
IDBP-716859
IDBP-716879
IDBP-811423
zinc finger protein 268
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:133181409-133214831
Strand Forward strand
Band q24.33
Transcripts
ENST00000228289 ENSP00000228289
ENST00000416488 ENSP00000409295
ENST00000500625 ENSP00000466629
ENST00000541009 ENSP00000439539
ENST00000546126 ENSP00000437410
ENST00000537973
ENST00000541211 ENSP00000442446
ENST00000541975 ENSP00000446153
ENST00000536899 ENSP00000438941
ENST00000539248 ENSP00000467781
ENST00000534953
ENST00000536435 ENSP00000444412
ENST00000542711 ENSP00000437858
ENST00000542986 ENSP00000443721
ENST00000588312 ENSP00000466622
ENST00000591951 ENSP00000464721
ENST00000592241 ENSP00000467922
ENST00000585488
ENST00000611984 ENSP00000479191
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001934 positive regulation of protein phosphorylation
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007346 regulation of mitotic cell cycle
GO:0008284 positive regulation of cell proliferation
GO:0008285 negative regulation of cell proliferation
GO:0008588 release of cytoplasmic sequestered NF-kappaB
GO:0030154 cell differentiation
GO:0030335 positive regulation of cell migration
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043497 regulation of protein heterodimerization activity
GO:0045597 positive regulation of cell differentiation
GO:0045732 positive regulation of protein catabolic process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis
GO:0071157 negative regulation of cell cycle arrest
GO:0071356 cellular response to tumor necrosis factor
GO:0090073 positive regulation of protein homodimerization activity
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_12627
Generic Transcription Pathway pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.183291
RefSeq NM_001165881 NM_001165882 NM_001165883 NM_001165884 NM_001165885 NM_001165886 NM_001165887 NM_003415 NM_152943
HUGO
OMIM
CCDS CCDS45012 CCDS53851 CCDS53852 CCDS53853 CCDS53854 CCDS59239 CCDS59240
HPRD 05300
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca