Version 5.4
Homo sapiens Gene: USP13
Summary
InnateDB Gene IDBG-66443.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol USP13
Gene Name ubiquitin specific peptidase 13 (isopeptidase T-3)
Synonyms IsoT-3; ISOT3
Species Homo sapiens
Ensembl Gene ENSG00000058056
Encoded Proteins
IDBP-66445
ubiquitin specific peptidase 13 (isopeptidase T-3)
IDBP-476787
ubiquitin specific peptidase 13 (isopeptidase T-3)
IDBP-480249
ubiquitin specific peptidase 13 (isopeptidase T-3)
IDBP-477708
ubiquitin specific peptidase 13 (isopeptidase T-3)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:179652755-179789401
Strand Forward strand
Band q26.33
Transcripts
ENST00000263966 ENSP00000263966
ENST00000482333
ENST00000497380 ENSP00000418651
ENST00000496897 ENSP00000417146
ENST00000497155 ENSP00000420057
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 40 experimentally validated interaction(s) in this database.
Experimentally validated
Total 40 [view]
Protein-Protein 40 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004197 cysteine-type endopeptidase activity
GO:0004221 ubiquitin thiolesterase activity
GO:0004843 ubiquitin-specific protease activity
GO:0005515 protein binding
GO:0008242 omega peptidase activity
GO:0008270 zinc ion binding
GO:0031625 ubiquitin protein ligase binding
GO:0036459 ubiquitinyl hydrolase activity
GO:0043130 ubiquitin binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006914 autophagy
GO:0008283 cell proliferation
GO:0010506 regulation of autophagy
GO:0030318 melanocyte differentiation
GO:0050821 protein stabilization
GO:0070536 protein K63-linked deubiquitination
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000056900
View Gene Order
ENSBTAG00000005946
Not yet available
Cross-References
SwissProt
TrEMBL H7C502
UniProt Splice Variant
Entrez Gene 8975
UniGene Hs.175322 Hs.604276
RefSeq NM_003940
HUGO HGNC:12611
OMIM 603591
CCDS CCDS3235
HPRD 04666
IMGT
EMBL AC007687 AC125604
GenPept
RNA Seq Atlas 8975

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca