Version 5.4
Homo sapiens Gene: MCF2L2
Summary
InnateDB Gene IDBG-66895.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MCF2L2
Gene Name MCF.2 cell line derived transforming sequence-like 2
Synonyms ARHGEF22
Species Homo sapiens
Ensembl Gene ENSG00000053524
Encoded Proteins
IDBP-66897
MCF.2 cell line derived transforming sequence-like 2
IDBP-385752
MCF.2 cell line derived transforming sequence-like 2
IDBP-385755
MCF.2 cell line derived transforming sequence-like 2
IDBP-484675
MCF.2 cell line derived transforming sequence-like 2
IDBP-473683
MCF.2 cell line derived transforming sequence-like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:183178043-183428778
Strand Reverse strand
Band q27.1
Transcripts
ENST00000328913 ENSP00000328118
ENST00000447025 ENSP00000388190
ENST00000414362 ENSP00000414131
ENST00000473233 ENSP00000420070
ENST00000478652
ENST00000464626
ENST00000468976
ENST00000488149
ENST00000475664
ENST00000459750
ENST00000492331
ENST00000482017 ENSP00000417345
ENST00000461074
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
Biological Process
GO:0032321 positive regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
Cellular Component
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.208267
RefSeq NM_015078
HUGO
OMIM
CCDS CCDS3243
HPRD 08308
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca