Version 5.4
Mus musculus Gene: Eif4e3
Summary
InnateDB Gene IDBG-703896.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Eif4e3
Gene Name eukaryotic translation initiation factor 4E member 3
Synonyms 1300018P11Rik; AI451927; eIF4E-3
Species Mus musculus
Ensembl Gene ENSMUSG00000093661
Encoded Proteins
IDBP-172807
eukaryotic translation initiation factor 4E member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163412:
EIF4E3 belongs to the EIF4E family of translational initiation factors that interact with the 5-prime cap structure of mRNA and recruit mRNA to the ribosome (Joshi et al., 2004 [PubMed 15153109]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:99625135-99666771
Strand Reverse strand
Band D3
Transcripts
ENSMUST00000032151 ENSMUSP00000032151
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
Biological Process
GO:0006413 translational initiation
GO:0006417 regulation of translation
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
GO:0005845 mRNA cap binding complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000163412
View Gene Order
ENSBTAG00000018862
Not yet available
Pathways
NETPATH
REACTOME
REACT_233584
Cytokine Signaling in Immune system pathway
REACT_198535
Antiviral mechanism by IFN-stimulated genes pathway
REACT_198533
ISG15 antiviral mechanism pathway
REACT_230745
Immune System pathway
REACT_198666
Interferon Signaling pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_115831
ISG15 antiviral mechanism pathway
REACT_115676
Antiviral mechanism by IFN-stimulated genes pathway
REACT_75790
Cytokine Signaling in Immune system pathway
REACT_25229
Interferon Signaling pathway
REACT_6900
Immune System pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9DBB5
TrEMBL
UniProt Splice Variant
Entrez Gene 66892
UniGene Mm.407252
RefSeq NM_025829
OMIM
CCDS CCDS20386
HPRD
IMGT
MGI ID MGI:1914142
MGI Symbol Eif4e3
EMBL AK005054 AK007268 AY628329 BC027014
GenPept AAH27014 AAT45741 BAB23780 BAB24928
RNA Seq Atlas 66892

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca