Version 5.4
Homo sapiens Gene: RASEF
Summary
InnateDB Gene IDBG-73397.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RASEF
Gene Name RAS and EF-hand domain containing
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000165105
Encoded Proteins
IDBP-73401
RAS and EF-hand domain containing
IDBP-73403
RAS and EF-hand domain containing
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the Rab family of GTPases that are involved in regulation of membrane traffic. The encoded protein contains an N-terminal EF-hand domain, a coiled-coil motif and a C-terminal Rab domain. A potential role as tumor suppressor has been indicated for this gene. [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:82979585-83063177
Strand Reverse strand
Band q21.32
Transcripts
ENST00000376447 ENSP00000365630
ENST00000340717 ENSP00000345651
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005509 calcium ion binding
GO:0005525 GTP binding
GO:0051015 actin filament binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0007155 cell adhesion
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
Cellular Component
GO:0005622 intracellular
GO:0016020 membrane
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000043003
View Gene Order
ENSBTAG00000021751
Not yet available
Cross-References
SwissProt Q8IZ41
TrEMBL
UniProt Splice Variant
Entrez Gene 158158
UniGene Hs.129136 Hs.657750 Hs.715184
RefSeq NM_152573 XM_005251731
HUGO HGNC:26464
OMIM 611344
CCDS CCDS6662
HPRD
IMGT
EMBL AK056176 AL499602 BC023566 CH471089
GenPept AAH23566 CAH70678 CAH70679 EAW62643
RNA Seq Atlas 158158

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca