Version 5.4
| Homo sapiens Gene: SLC4A10 | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-73631.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | SLC4A10 | ||||||||||||||||||
| Gene Name | solute carrier family 4, sodium bicarbonate transporter, member 10 | ||||||||||||||||||
| Synonyms | |||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000144290 | ||||||||||||||||||
| Encoded Proteins |
solute carrier family 4, sodium bicarbonate transporter, member 10
solute carrier family 4, sodium bicarbonate transporter, member 10
solute carrier family 4, sodium bicarbonate transporter, member 10
solute carrier family 4, sodium bicarbonate transporter, member 10
solute carrier family 4, sodium bicarbonate transporter, member 10
solute carrier family 4, sodium bicarbonate transporter, member 10
|
||||||||||||||||||
| Protein Structure | |||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene belongs to a small family of sodium-coupled bicarbonate transporters (NCBTs) that regulate the intracellular pH of neurons, the secretion of bicarbonate ions across the choroid plexus, and the pH of the brain extracellular fluid. The protein encoded by this gene was initially identified as a sodium-driven chloride bicarbonate exchanger (NCBE) though there is now evidence that its sodium/bicarbonate cotransport activity is independent of any chloride ion countertransport under physiological conditions. This gene is now classified as a member A10 of the SLC4 family of transmembrane solute carriers. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010] |
||||||||||||||||||
| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 2:161424332-161985282 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | q24.2 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
|
||||||||||||||||||
| Gene Ontology | |||||||||||||||||||
Molecular Function |
|
||||||||||||||||||
| Biological Process |
|
||||||||||||||||||
| Cellular Component |
|
||||||||||||||||||
| Orthologs | |||||||||||||||||||
|
Species
Mus musculus
Bos taurus
|
Gene ID
Gene Order
Not yet available
|
||||||||||||||||||
| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
Bicarbonate transporters pathway
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
Transmembrane transport of small molecules pathway
SLC-mediated transmembrane transport pathway
|
||||||||||||||||||
| KEGG | |||||||||||||||||||
| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | |||||||||||||||||||
| TrEMBL | C9J240 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 57282 | ||||||||||||||||||
| UniGene | Hs.333958 Hs.623881 | ||||||||||||||||||
| RefSeq | NM_001178015 NM_001178016 NM_022058 | ||||||||||||||||||
| HUGO | HGNC:13811 | ||||||||||||||||||
| OMIM | 605556 | ||||||||||||||||||
| CCDS | CCDS46438 CCDS54411 CCDS54412 | ||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AC008063 AC009487 AC062022 AC092654 AC092841 AC096654 | ||||||||||||||||||
| GenPept | |||||||||||||||||||
| RNA Seq Atlas | 57282 | ||||||||||||||||||