Version 5.4
Homo sapiens Gene: CENPP
Summary
InnateDB Gene IDBG-76133.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CENPP
Gene Name centromere protein P
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000188312
Encoded Proteins
IDBP-76135
centromere protein P
IDBP-76137
centromere protein P
IDBP-76139
centromere protein P
IDBP-811190
centromere protein P
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary CENPP is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:92325484-92620533
Strand Forward strand
Band q22.31
Transcripts
ENST00000375587 ENSP00000364737
ENST00000375579 ENSP00000364729
ENST00000375576 ENSP00000364726
ENST00000618653 ENSP00000477821
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0000278 mitotic cell cycle
GO:0006334 nucleosome assembly
GO:0034080 centromere-specific nucleosome assembly
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0005654 nucleoplasm
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000021391
View Gene Order
ENSBTAG00000011814
Not yet available
Pathways
NETPATH
REACTOME
REACT_22186
Deposition of new CENPA-containing nucleosomes at the centromere pathway
REACT_150425
Resolution of Sister Chromatid Cohesion pathway
REACT_682
Mitotic Prometaphase pathway
REACT_150471
Separation of Sister Chromatids pathway
REACT_22172
Chromosome Maintenance pathway
REACT_22344
Nucleosome assembly pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_1275
Mitotic Anaphase pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_150314
Mitotic Metaphase and Anaphase pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q6IPU0
TrEMBL X6R9C8
UniProt Splice Variant
Entrez Gene 401541
UniGene Hs.660395 Hs.674179 Hs.713775
RefSeq NM_001012267 NM_001286971
HUGO HGNC:32933
OMIM 611505
CCDS CCDS35063 CCDS69618
HPRD
IMGT
EMBL AK091247 AK092603 AL136097 AL137848 AL157827 BC071726 CH471089
GenPept AAH71726 BAG52317 BAG52579 CAI12591 CAI12592 CAI12594 CAI16210 CAI16699 EAW62825
RNA Seq Atlas 401541

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca